Gyurakku
ギュラック
Drug Type
Irritable bowel syndrome (IBS) relief medicine (polycarbophil calcium)
Form
Tablets
Indication
Relief of the following symptoms of irritable bowel syndrome: diarrhea and constipation that come back again and again or alternate, with abdominal pain or abdominal discomfort (only for people who have been diagnosed and treated by a doctor before).
Active Ingredients (per 3 tablets (daily dose))
Polycarbophil calcium 1,500 mg (as dried substance)
Inactive Ingredients
Cellulose, carmellose (CMC), hydroxypropyl cellulose, magnesium stearate, hypromellose, macrogol, titanium oxide, polyvinyl acetal diethylaminoacetate, carnauba wax
Instructions for Use
- ✓Take the following amount after meals, with water.
| Age | Dose per use | Times per day |
|---|---|---|
| Adults (15 years and older) | 1 tablet | 3 times daily |
| Under 15 years, or 75 years and older | Do not use | — |
- ✓Follow the recommended dosage strictly.
- ✓Take with a full glass of water (about 180 mL). (If you do not take it with water, it may get stuck in your throat or esophagus.)
- ✕Do not split or crush the tablet, and do not take it with swallowing aids such as jelly or thickeners. (It may swell in your throat or esophagus and get stuck.)
- ✕Do not take it at the same time as health foods in tablet or capsule form. (They may get stuck in your throat or esophagus.)
- ✓Even if your symptoms improve, take it for no more than 4 weeks.
- ✓To remove a tablet from the PTP sheet, press firmly on the raised side of the sheet with your fingertip to break the aluminum foil on the back, then take out the tablet. Do not swallow the PTP sheet, as it may puncture the esophageal lining and cause serious injury.
- ✕Do not use this product if you:
- (1) Have never been diagnosed or treated for irritable bowel syndrome (IBS) by a doctor.
- (2) Are not sure whether this is a recurrence of IBS (for example, your symptoms this time are different from when you were diagnosed and treated for IBS before).
- (3) Have any of the following symptoms: needing to go to the toilet to pass stool, or abdominal pain, at night, such as while sleeping; fever; joint pain; stool with mucus and blood (rectal bleeding); repeated severe diarrhea; sudden severe diarrhea; abdominal pain that does not get better after a bowel movement; vomiting; or unexpected weight loss of 3 kg or more within 6 months.
- (4) Have ever had colorectal cancer or inflammatory bowel disease (Crohn's disease, ulcerative colitis, etc.).
- (5) Have had abdominal surgery and now have any of the following: severe abdominal pain, no passing of gas, or severe constipation with abdominal bloating (symptoms like a bowel obstruction). (This product may cause a bowel obstruction.)
- (6) Are being treated for any of the following: an acute abdominal disease (appendicitis, intestinal bleeding, ulcerative colitis, etc.), hypercalcemia, kidney stones, or kidney failure (except while on dialysis).
- (7) Have ever had an allergic reaction to this product or any of its ingredients.
- (8) Have difficulty swallowing (you feel it is hard to swallow food, etc.).
- (9) Are under 15 years of age, or are 75 years of age or older.
- ✕Do not take medicines containing any of the following while taking this product: IBS symptom relievers (trimebutine maleate, etc.), active vitamin D preparations (alfacalcidol, etc.), calcium preparations (calcium lactate, etc.), cardiac glycosides (digoxin, etc.), antibiotics (tetracycline, norfloxacin, etc.), proton pump inhibitors (omeprazole, etc.), H2 blockers (famotidine, ranitidine, etc.), or antacids (aluminum hydroxide gel, magnesium hydroxide, etc.).
- ✕Do not use continuously for a long time.
- ⚠Consult a doctor or pharmacist before use if you:
- (1) Are under medical treatment.
- (2) Are pregnant or possibly pregnant.
- (3) Are 50 years of age or older.
- (4) Have anemia.
- (5) Have ever had an allergic reaction to a medicine.
- (6) Have been diagnosed with diabetes, thyroid disease, or hyperparathyroidism.
- (7) Are prone to hypercalcemia (such as people with excess vitamin D).
- (8) Have no or reduced stomach acid secretion, or may have this.
- (9) Have a family member with colorectal cancer or inflammatory bowel disease.
- (10) Have severe abdominal pain or constipation.
- (11) Are on dialysis.
- ✓Stop use immediately and consult a doctor or pharmacist — bringing this package insert with you — if any of the following appear after taking this product, as they may be side effects:
- Skin: Rash or itching
- Gastrointestinal: Nausea/vomiting, dry mouth, abdominal bloating, diarrhea, constipation, abdominal pain, or rumbling stomach
- Liver: General fatigue, or yellowing of the skin or whites of the eyes
- Other: Swelling, blood in urine, protein in urine, headache, sudden high fever, chills, or sore throat
- ✓Stop use and consult a doctor or pharmacist — bringing this package insert with you — if symptoms do not improve after 2 weeks.
- ✓Store in a cool, dry place away from direct sunlight. Keep out of reach of children. Do not transfer to another container (this can cause mistaken use or affect quality). Do not use after the expiry date.
Additional Information
Contains polycarbophil calcium. It holds water in the intestine and brings stools back to normal.
The maker's check sheet (not the package insert) explains that "repeated severe diarrhea" means diarrhea 3 times a day for 1 week or longer, and that "severe constipation" means 2 or fewer bowel movements a week.
Sources & Documents
- Japanese product page
- Japanese PDF
- Suitability Checklist
- Last verified: October 14, 2026
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For informational purposes only. Always consult a doctor or pharmacist before taking any medication.