Loxonin S Premium Fine

Loxonin S Premium Fine

ロキソニンSプレミアムファイン

Pain Relief
Class 1 — Pharmacies only · Pharmacist required
Drug Type

NSAID analgesic and antipyretic (loxoprofen)

Form

Tablets

Indication

Relief of headache, shoulder stiffness pain, menstrual pain, toothache, post-extraction pain, sore throat, joint pain, neuralgia, back pain, muscle pain, bruising pain, earache, fracture pain, sprain pain, and traumatic pain; and reduction of fever and chills

Active Ingredients (per 2 tablets)

• Loxoprofen sodium hydrate 68.1mg (60mg as anhydrate) • Paeonia dry extract 36mg (252mg as whole crude drug) • Hesperidin 30mg • Magnesium aluminometasilicate 100mg

Inactive Ingredients

D-mannitol, cellulose, croscarmellose sodium, hydroxypropylcellulose, magnesium stearate, hypromellose, titanium oxide, macrogol, red ferric oxide, carnauba wax

Instructions for Use

  • ✓Take with water or lukewarm water. Avoid taking on an empty stomach. Allow at least 4 hours between doses.
Age Dose per use Times per day
Adults (15 years and older) 2 tablets Up to 2 times daily (a 3rd dose may be taken if symptoms return)
Under 15 years Do not use —
  • ✕Do not take if you have had an allergic reaction to this product or any of its ingredients.
  • ✕Do not take if you have experienced an asthma attack triggered by this product, other analgesics or antipyretics, or cold medicines.
  • ✕Do not take if you are under 15 years of age.
  • ✕Do not take if you are pregnant and within 12 weeks of your due date.
  • ✕Do not use with other analgesics/antipyretics, cold medicines, or sedatives.
  • ✕Do not drink alcohol before or after taking this medication.
  • ✕Do not take for an extended period.
  • ✓If any of the following occur after taking, stop immediately and consult a physician, dentist, pharmacist, or registered salesperson: skin rash, redness, itching, or bruising; nausea, vomiting, loss of appetite, stomach discomfort, stomach pain, mouth sores, heartburn, heaviness in the stomach, gastrointestinal bleeding, abdominal pain, diarrhea, or bloody stool; dizziness; palpitations; shortness of breath; or blurred vision, tinnitus, swelling, nosebleed, bleeding from the gums, difficulty stopping bleeding, bleeding, back pain, excessive drop in body temperature, or general malaise.
  • ✓If dry mouth, constipation, or diarrhea persists or worsens after taking, stop use and consult a physician, pharmacist, or registered salesperson.
  • ✓Seek immediate medical attention if you experience itchy skin, hives, hoarseness, sneezing, itchy throat, difficulty breathing, palpitations, or clouding of consciousness (possible anaphylactic shock); high fever, bloodshot eyes, eye discharge, blistering or erosion of the lips, oral mucosa, or genitals, sore throat, or widespread rash or skin redness, or small pustules on reddened skin (possible Stevens-Johnson syndrome, toxic epidermal necrolysis, or erythema multiforme, or acute generalized exanthematous pustulosis); widespread skin redness, systemic rash, fever, lethargy, or swelling of lymph nodes in the neck, armpits, or groin (possible drug-induced hypersensitivity syndrome); fever, itching, rash, jaundice, brown urine, general malaise, or loss of appetite (possible liver damage); fever, rash, decreased urine output, generalized swelling, general malaise, joint pain, or diarrhea (possible kidney disorder); severe headache with neck stiffness, fever, or nausea and vomiting (possible aseptic meningitis); pressure-like chest pain, shortness of breath, or cold sweats (possible myocardial infarction); sudden loss of or decreased consciousness, weakness moving one side of the body, headache, vomiting, dizziness, difficulty speaking, or speech impairment (possible cerebrovascular disorder); shortness of breath or difficulty breathing after mild exertion, dry coughing, or fever (possible interstitial pneumonia); wheezing or difficulty breathing (possible asthma); bruising, nosebleed, bleeding from the gums, fever, pale skin or mucous membranes, fatigue, palpitations, shortness of breath, feeling sick and fainting, or bloody urine (possible aplastic anemia); sudden high fever, chills, or sore throat (possible agranulocytosis); or sudden decrease in white blood cells, red blood cells, or platelets — fatigue, paleness, shortness of breath, fever, bleeding tendency (possible blood disorder).
  • ⚠Consult a physician, dentist, pharmacist, or registered salesperson before use if you: are currently receiving medical or dental treatment; are pregnant or may be pregnant; are nursing; are elderly; have had an allergic reaction to any drug; or have been diagnosed with or have a history of stomach or duodenal ulcers, blood disease, kidney disease, liver disease, heart disease, high blood pressure, bronchial asthma, systemic lupus erythematosus, mixed connective tissue disease, ulcerative colitis, or Crohn's disease.
  • ✓Seek immediate medical attention if any of the following serious symptoms appear:
  • • Shock (anaphylaxis): Itching of skin, hives, hoarseness, sneezing, itchy throat, difficulty breathing, palpitations, or clouding of consciousness immediately after use.
  • • Stevens-Johnson syndrome / toxic epidermal necrolysis: High fever, redness of eyes, eye discharge, sores on lips, sore throat, or widespread rash or redness on skin that persists or rapidly worsens.
  • • Liver disorder: Fever, itching, rash, jaundice (yellowing of the skin or whites of the eyes), dark urine, general fatigue, or loss of appetite.
  • • Kidney disorder: Fever, rash, decreased urine output, swelling throughout the body, general fatigue, joint pain, or diarrhea.
  • • Aseptic meningitis: Severe headache with stiff neck, fever, nausea, or vomiting. (More common in people with systemic lupus erythematosus or mixed connective tissue disease.)
  • • Myocardial infarction: Squeezing chest pain, difficulty breathing, or cold sweat.
  • • Cerebrovascular disorder: Sudden onset of decreased or loss of consciousness, difficulty moving one side of the body, headache, vomiting, dizziness, slurred speech, or difficulty finding words.
  • • Interstitial pneumonia: Shortness of breath with climbing stairs or slight exertion, dry cough, or fever that appears suddenly or persists.
  • • Asthma: Wheezing or whistling breath sounds, or difficulty breathing.
  • • Aplastic anemia: Bruising, nosebleed, bleeding gums, fever, pale skin or mucous membranes, fatigue, palpitations, shortness of breath, feeling faint, or blood in urine.
  • • Agranulocytosis: Sudden high fever, chills, or sore throat.
  • ✓Strictly follow the prescribed dosage.
  • ✓When removing the tablet from the PTP sheet, press the convex side firmly to break the foil on the back. Do not swallow the PTP sheet.
  • ✓If symptoms do not improve after 1 to 2 doses, stop use and consult a physician, dentist, pharmacist, or registered salesperson.

Sources & Documents

Related Medicines

Check Price on Amazon Japan
Share this page:

For informational purposes only. Always consult a doctor or pharmacist before taking any medication.